Everything about The Institute For Genomic Research totally explained
The Institute for Genomic Research (
TIGR) was a
non-profit genomics research institute founded in
1992 by
Craig Venter in
Rockville, Maryland,
United States. It is now a part of the
J. Craig Venter Institute.
TIGR
sequenced the first
genome of a free-living organism, the
bacterium Haemophilus influenzae, in 1995. This landmark project, led by TIGR scientist Robert Fleischmann, led to an explosion of genome sequencing projects, all using the whole-genome sequencing technique pioneered earlier but never used for a whole bacterium until TIGR's project. TIGR scientist Claire Fraser led the projects to sequence the second bacterium,
Mycoplasma genitalium in 1996, and less than a year later TIGR's Carol Bult led the project to sequence the first genome of an
Archaeal species,
Methanococcus jannaschii. In 1999 TIGR published the sequence of the
radioresistant polyextremophile Deinococcus radiodurans.
TIGR went on to become the world's leading center for microbial genome sequencing, and it also participated in the
Human Genome Project and many other genome projects. Its
bioinformatics group developed many of the pioneering software algorithms that were used to analyze these genomes, including the automatic gene finder
GLIMMER and the genome alignment program
MUMmer.
In late 2006, TIGR became a division of the
J. Craig Venter Institute (JCVI). In March/April of 2007 the divisions were dissolved and TIGR, along with the
Center for the Advancement of Genomics, J. Craig Venter Science Foundation, Joint Technology Center and the Institute for Biological Energy Alternatives (IBEA), were absorbed under the JCVI name.
After presiding over the organization for nearly 10 years
Dr. Fraser (ex-wife of
Craig Venter) resigned her position and left the organization on April 20th, 2007.
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